Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study

Harding-Esch, E., Jofre-Bonet, M., Dhanjal, J. K., Burr, S., Edwards, T., Holland, M., Sillah, A., West, S., Lietman, T., Keenan, J., Mabey, D. & Bailey, R. (2015). Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study. PLoS Neglected Tropical Diseases, 9(4), e0003670. doi: 10.1371/journal.pntd.0003670

[img]
Preview
Text - Accepted Version
Available under License Creative Commons: Attribution International Public License 4.0.

Download (521kB) | Preview

Abstract

Mass drug administration (MDA) treatment of active trachoma with antibiotic is recommended to be initiated in any district where the prevalence of trachoma inflammation, follicular (TF) is ≥10% in children aged 1-9 years, and then to continue for at least three annual rounds before resurvey. In The Gambia the PRET study found that discontinuing MDA based on testing a sample of children for ocular Chlamydia trachomatis(Ct) infection after one MDA round had similar effects to continuing MDA for three rounds. Moreover, one round of MDA reduced disease below the 5% TF threshold. We compared the costs of examining a sample of children for TF, and of testing them for Ct, with those of MDA rounds.

Item Type: Article
Uncontrolled Keywords: The Gambia, Trachoma, Chlamydia trachomatis, Cost, Treatment
Subjects: H Social Sciences > HB Economic Theory
R Medicine > RC Internal medicine
Divisions: School of Social Sciences > Department of Economics
URI: http://openaccess.city.ac.uk/id/eprint/11691

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics