Optimization of a horizontal slot waveguide biosensor to detect DNA hybridization

Viphavakit, C., Komodromos, M., Themistos, C., Mohammed, W. S., Kalli, K. & Rahman, B. M. (2015). Optimization of a horizontal slot waveguide biosensor to detect DNA hybridization. Applied Optics, 54(15), pp. 4881-4888. doi: 10.1364/AO.54.004881

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Abstract

A full-vectorial H-field formulation-based finite element approach is used to optimize a biosensor structure incorporating a horizontal slot waveguide. It is designed to detect DNA hybridization through the change of the effective index of the waveguide structure. The key parameters, such as normalized power confinement, power density, change in effective index, and sensitivity are presented by optimizing the device parameters of the slot waveguide. It is shown here that a 90.0 μm long compact Mach–Zehnder section can be designed with horizontal slot waveguide to detect DNA hybridization and for a ring resonator arrangement a sensitivity of 893.5 nm/RIU is obtained.

Item Type:	Article
Additional Information:	© 2014 Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modifications of the content of this paper are prohibited.
Subjects:	T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:	School of Engineering & Mathematical Sciences > Engineering
URI:	http://openaccess.city.ac.uk/id/eprint/12218

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