Optical analysis of lithium carbonate: Towards the development of a portable lithium blood level analyzer for bipolar disorder patients

May, J.M., Hickey, M., Triantis, I., Palazidou, E. & Kyriacou, P. A. (2014). Optical analysis of lithium carbonate: Towards the development of a portable lithium blood level analyzer for bipolar disorder patients. Paper presented at the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, 26-08-2014 - 30-08-2014, Chicago, USA.

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Abstract

Lithium medication is the gold standard of treatment in Bipolar Disorder patients, preventing and reducing mood swings and suicidality. However, despite its effectiveness, it is a potentially hazardous drug requiring regular monitoring of blood levels to ensure toxic levels are not reached. This paper describes the first steps towards developing a new portable device that can be used by Bipolar Disorder patients to facilitate the analysis of lithium blood levels at home. Solutions of lithium carbonate have been optically fingerprinted using a high-end spectrophotometer. Preliminary measurements indicate that while the visible to near infrared region of the absorption spectra fall heavily within the water band, measurements in the Ultraviolet region show a strong distinction between different lithium concentrations. The optical spectra of Lithium in the 220 nm to 230 nm region demonstrated the ability to differentiate between concentrations representing those found in patients.

Item Type: Conference or Workshop Item (Paper)
Additional Information: © 2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Subjects: R Medicine > RC Internal medicine
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: School of Engineering & Mathematical Sciences > Engineering
URI: http://openaccess.city.ac.uk/id/eprint/12963

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