Investigation of photoplethysmography and Near Infrared Spectroscopy for the assessment of tissue blood perfusion

Abay, T. & Kyriacou, P. A. (2014). Investigation of photoplethysmography and Near Infrared Spectroscopy for the assessment of tissue blood perfusion. Paper presented at the 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, 26-08-2014 - 30-08-2014, Chicago, USA.

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Pulse Oximetry (PO) and Near Infrared Spectroscopy (NIRS) are among the most widely adopted optical techniques for the assessment of tissue perfusion. PO estimates arterial oxygen saturation (SpO<inf>2</inf>) by exploiting light attenuations due to pulsatile arterial blood (AC) and constant absorbers (DC) at two different wavelengths. NIRS processes the attenuations of at least two wavelengths to calculate concentrations of Deoxygenated ([HHb]), Oxygenated ([HbO<inf>2</inf>]), Total Haemoglobin ([tHb]) and Tissue Oxygenation Index (TOI). In this work we present the development and evaluation of a reflectance PPG probe and processing system for the assessment of tissue perfusion. The system adopts both Pulse Oximetry and NIRS principles to calculate SpO<inf>2</inf>, [HHb], and [HbO<inf>2</inf>] and [tHb]. The system has been evaluated on the forearm of 10 healthy volunteers during cuff-induced vascular occlusions. The presented system was able to estimate SpO<inf>2</inf>, [HHb], [HbO<inf>2</inf>] and [tHb], showing good agreement with state-of-the-art NIRS and conventional PO.

Item Type: Conference or Workshop Item (Paper)
Additional Information: © 2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Subjects: R Medicine > RC Internal medicine
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: School of Engineering & Mathematical Sciences > Engineering

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