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LFP and oscillations - what do they tell us?

Friston, K. J., Bastos, A. M., Pinotsis, D. A. ORCID: 0000-0002-6865-8103 and Litvak, V. (2014). LFP and oscillations - what do they tell us?. Current Opinion in Neurobiology, 31, pp. 1-6. doi: 10.1016/j.conb.2014.05.004

Abstract

This review surveys recent trends in the use of local field potentials—and their non-invasive counterparts—to address the principles of functional brain architectures. In particular, we treat oscillations as the (observable) signature of context-sensitive changes in synaptic efficacy that underlie coordinated dynamics and message-passing in the brain. This rich source of information is now being exploited by various procedures—like dynamic causal modelling—to test hypotheses about neuronal circuits in health and disease. Furthermore, the roles played by neuromodulatory mechanisms can be addressed directly through their effects on oscillatory phenomena. These neuromodulatory or gain control processes are central to many theories of normal brain function (e.g. attention) and the pathophysiology of several neuropsychiatric conditions (e.g. Parkinson's disease).

Publication Type: Article
Additional Information: 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license(http://creativecommons.org/licenses/by/3.0/).
Departments: School of Arts & Social Sciences > Psychology
URI: http://openaccess.city.ac.uk/id/eprint/19427
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