Tracking neutrophils in zebrafish: the use of synthetic data sets

Reyes-Aldasoro, C. C., Henry, K. M. & Renshaw, S. A. (2012). Tracking neutrophils in zebrafish: the use of synthetic data sets. Paper presented at the Medical Image Understanding and Analysis, 09-07-2012 - 11-07-2012, Swansea, UK.

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In this work we present a series of data sets that model the behaviour of neutrophils as observed with a confocal microscope. The data sets describe important characteristics of the migration of neutrophils such as collisions and path tortuosity as well as different levels of background noise. Neutrophil trajectories were manually defined, and Gaussian shapes similar to those of real data sets were assigned to each position of a neutrophil. The availability of synthetic data sets such as the ones proposed here, together with appropriate gold standards will benefit those wanting to test the robustness and accuracy of segmentation and tracking algorithms.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > RC Internal medicine
T Technology > T Technology (General)
Divisions: School of Engineering & Mathematical Sciences > Engineering

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