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Preliminary evaluation of a new fibre-optic cerebral oximetry system

Phillips, J. P., Langford, R. M., Kyriacou, P. A. & Jones, D. P. (2008). Preliminary evaluation of a new fibre-optic cerebral oximetry system. Physiological Measurement, 29(12), pp. 1383-1396. doi: 10.1088/0967-3334/29/12/003


A new system for measuring the oxygen saturation of blood within tissue has been developed, for a variety of patient monitoring applications. A particular unmet need is in the central nervous system, and this project aims to devise a means for measuring blood oxygen saturation in the brain tissue of patients recovering from neurosurgery or head injury. Coupling light sources and a photodetector to optical fibres results in a probe small enough to pass through a cranial bolt of the type already in use for intra-cranial pressure monitoring. The development and evaluation of a two-wavelength fibre-optic reflectance photoplethysmography (PPG) system are described. It was found that good quality red and near-infrared PPG signals could be obtained from the finger using a fibre-optic probe. Experiments were conducted to find the inter-fibre spacings that yield signals most suitable for calculating oxygen saturation. Reliable signals could be obtained for inter-fibre spacings between 2 mm and 5 mm, the latter being the size of the maximum aperture in the cranial bolt. A preliminary measurement from human brain tissue is also presented.

Publication Type: Article
Publisher Keywords: cerebral, brain, oximetry, photoplethysmography, fibre-optic, cranial bolt
Subjects: R Medicine
T Technology > TA Engineering (General). Civil engineering (General)
Departments: School of Science & Technology
School of Science & Technology > Engineering
SWORD Depositor:
[thumbnail of CRO2008 J P Phillips, et al. (2008) Preliminary evaluation of a new fibre-optic cerebral oximetry system, Physiological Measurement, 29,1383-1396 .pdf]
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