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Investigation of Photoplethysmographic Changes using a Static Compression Model of Spinal Cord Injury

Phillips, J. P., George, K., Kyriacou, P. A. & Langford, R. M. (2009). Investigation of Photoplethysmographic Changes using a Static Compression Model of Spinal Cord Injury. Paper presented at the EMBC 2009. Annual International Conference of the IEEE, 3-6 Sept. 2009, Minneapolis, MN. doi: 10.1109/IEMBS.2009.5334166


Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fiber-optic photoplethysmography system was used to investigate whether pulsation of the small arteries in the spinal cord occurred before, during and after compressive loads were applied to the tissue. It was found that the signal amplitudes were reduced and this reduction persisted for at least five minutes after the compression ceased. It is hoped that results from this preliminary study may improve knowledge of the mechanism of spinal cord injury.

Publication Type: Conference or Workshop Item (Paper)
Additional Information: © 2009 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Publisher Keywords: Science & Technology; Technology; Engineering, Biomedical; Engineering; APOPTOSIS; RATS
Departments: School of Science & Technology
School of Science & Technology > Engineering
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