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An optical fiber photoplethysmographic system for central nervous system tissue

Phillips, J. P., Kyriacou, P. A., George, K. , Priestley, J. V. & Langford, R. M. (2006). An optical fiber photoplethysmographic system for central nervous system tissue. Paper presented at the 28th Annual Conference of the IEEE Engineering in Medicine and Biology Society, 31 Aug - 3 Sep 2006, New York, USA.


A new system for measuring the oxygen saturation of blood within tissue has been developed, for a number of potential patient monitoring applications. This proof of concept project aims to address the unmet need of real-time measurement of oxygen saturation in the central nervous system (CNS) for patients recovering from neurosurgery or trauma, by developing a fiber optic signal acquisition system for internal placement through small apertures. The development and testing of a two-wavelength optical fiber reflectance photoplethysmography (PPG) system is described. It was found that good quality red and near-infrared PPG signals could be consistently obtained from the human fingertip (n=6) and rat spinal cord (n=6) using the fiber optic probe. These findings justify further development and clinical evaluation of this fiber optic system.

Publication Type: Conference or Workshop Item (Paper)
Additional Information: © 2006 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Subjects: R Medicine > RC Internal medicine
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Departments: School of Science & Technology > Engineering
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