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Photoplethysmography: Towards a non-invasive pressure measurement technique

Njoum, H. & Kyriacou, P. A. (2016). Photoplethysmography: Towards a non-invasive pressure measurement technique. In: IEEE. 2016 IEEE 38th Annual International Conference of the Engineering in Medicine and Biology Society (EMBC), 16-22 Aug 2016, Orlando, USA. doi: 10.1109/EMBC.2016.7590776


There is a need for a non-invasive and continuous blood pressure monitor. Photoplethysmography (PPG) is one of the techniques that were investigated for this purpose in an in vitro model where the relationship between the PPG and pressure-volume (P-V) changes was investigated. Pressure and red (R) infrared (IR) PPG signals were recorded continuously in an arterial model that simulates fluid flow utilizing a pulsatile pump. Flow rates were controlled through three set-points of pumping frequencies at low and high stroke volumes. Normalized Pulse Volume (NPV) is defined as the light intensity ratio at each wavelength, R (NPVR) and IR (NPVIR). Adjusted Pulse Volume (APV) was determined for both wavelengths. It was found that the optimum method for estimation of the pulsatile volume is through APV, which has a remarkable correlation (r2=0.99, p<0.001) with the assumed exponential P-V model. APV obtained significantly better fit when compared to NPVIR (r2=0.73, z=25.85, p<0.001) and NPVR (r2=0.95, z=12.26, p<0.001). Our preliminary findings emphasize the potential of APV as a non-invasive continuous method of blood pressure measurement.

Publication Type: Conference or Workshop Item (Paper)
Additional Information: © 2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Publisher Keywords: Pressure measurement, Blood pressure, In vitro, Electron tubes, Biomedical monitoring, Pumps, Fluids
Subjects: T Technology > TK Electrical engineering. Electronics Nuclear engineering
Departments: School of Science & Technology > Engineering
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