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Comparison of glistenings formation and their effect on forward light scatter between the Acrysof SN60WF and Eternity Natural Uni NW-60 intraocular lenses

Philippaki, E., O'Brart, D. P. and Hull, C. ORCID: 0000-0002-2205-4443 (2020). Comparison of glistenings formation and their effect on forward light scatter between the Acrysof SN60WF and Eternity Natural Uni NW-60 intraocular lenses. BMJ Open Ophthalmology, 5(1), e000399. doi: 10.1136/bmjophth-2019-000399

Abstract

Aims: To compare the characteristics of glistenings and forward light scatter between the Alcon Acrysof SN60WF and Santen Eternity Natural Uni NW-60 intraocular lenses (IOLs).

Methods: Five Acrysof SN60WF and five Eternity Natural Uni NW-60 IOLs were studied. All IOLs were single piece blue blockers with the same dioptric power (20D) and optic diameter (6.0 mm). Glistenings were induced by a thermal accelerated ageing process. Glistenings were objectively quantified using bespoke image processing software. The angular distribution of forward light scatter was measured using an optical bench system and the straylight parameter calculated from the light scatter function.

Results: The median increase in the number of glistenings was 15 and 525 for the Eternity and Acrysof IOLs, respectively, which was statistically significantly different (p=0.012). Median glistenings diameter was 23.8 μm (Acrysof) and 32.8 μm (Eternity). Four (80%) of the Acrysof lenses had straylight values higher than a 20-year-old CIE standard glare observer and in two cases the straylight exceeded that of the 70-year-old CIE standard glare observer. None of the Eternity lenses had straylight values that exceeded the value for the 20-year-old CIE standard glare observer.

Conclusions: The Eternity Natural Uni NW-60 IOLs resisted the induction of glistenings more than the Acrysof SN60WF IOLs. Although the Acrysof IOLs developed smaller glistenings than the Eternity IOLs, there were sufficient numbers to produce a higher straylight parameter.

Publication Type: Article
Additional Information: This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Subjects: R Medicine > RE Ophthalmology
Departments: School of Health Sciences
Date Deposited: 24 Mar 2020 12:12
URI: https://openaccess.city.ac.uk/id/eprint/23824
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