City Research Online

Fast versus gradual adaptation of soft monthly contact lenses in neophyte wearers

Wolffsohn, J. S., Ghorbani-Mojarrad, N., Vianya-Estopa, M., Nagra, M., Huntjens, B. ORCID: 0000-0002-4864-0723, Terry, L., Sweeney, L. E., Dutta, D., Joshi, M. R., Wright, D., Bruce, H., Hallam, E., Jolly, L., Chung, Y. B., En Tsen, J. R., Bishop, A., Davison, R. and Maldonado-Codina, C. (2021). Fast versus gradual adaptation of soft monthly contact lenses in neophyte wearers. Contact Lens and Anterior Eye, 101469. doi: 10.1016/j.clae.2021.101469

Abstract

Aim: To determine if a gradual adaptation period is necessary for neophytes when fitted with modern hydrogel or silicone hydrogel reusable disposable contact lenses.

Method: Across four sites, 74 neophytes (18-28 years) were randomly assigned to a reusable lens: Proclear® (hydrogel) or Biofinity® (silicone hydrogel) and an adaptation schedule: fast (10 hours wear from the first day) or gradual (4 hours on the first day, increasing their wear time by 2 hours on each subsequent day until they had reached 10 hours). Masked investigators graded ocular surface physiology and non-invasive tear breakup time (NIBUT) and a range of comfort, vision and lens handling subjective ratings (0-100 visual analogue scales) were recorded at the baseline visit and after 10 hours of lens wear, 4-6 days and 12-14 days after lens fitting. Subjective scores were also repeated after 7 days.

Results: There was no difference (p>0.05) in ocular surface physiology or NIBUT between fast and gradual adaptation groups at any time point in either lens type with the exception of increased corneal staining (p=0.019) in the silicone hydrogel fast adaptation group after 4-6 days. Subjective scores were also similar across the visits and lens types with the exception of ‘lens awareness’ (p=0.019) which was less in the gradual versus the fast adaptation silicone hydrogel lens group at 12-14 days.

Conclusion: There seems to be no clinical benefit for recommending a gradual adaptation period in new wearers fitted with modern soft reusable disposable contact lenses. The findings of this work add to a growing body of evidence suggesting that such advice is unnecessary in regular soft contact lens wear, which has important ramifications for the initial clinical management of these patients.

Publication Type: Article
Additional Information: © 2021 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Publisher Keywords: Soft contact lens, reusable, adaptation, neophyte, fast, gradual
Subjects: R Medicine > RE Ophthalmology
Departments: School of Health Sciences > Optometry & Visual Science
Date available in CRO: 01 Jun 2021 11:31
Date deposited: 1 June 2021
Date of acceptance: 9 May 2021
Date of first online publication: 22 May 2021
URI: https://openaccess.city.ac.uk/id/eprint/26211
[img] Text - Accepted Version
This document is not freely accessible until 22 May 2022 due to copyright restrictions.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

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