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Improving sepsis screening and care in a developing nation health setting: A description of implementation

Alberto, L., Marshall, A. P., Walker, R. M. , Palizas, F. & Aitken, L. M. ORCID: 0000-0001-5722-9090 (2021). Improving sepsis screening and care in a developing nation health setting: A description of implementation. Nursing and Health Sciences, 23(4), pp. 936-947. doi: 10.1111/nhs.12884


Evidence on sepsis screening and care in developing nations is insufficient to inform implementation practices in hospital wards. The aim of this multi-method study was to describe and evaluate the implementation of a three-step intervention (sepsis screening, alert activation, care) in five wards in Argentina in 2017. The implementation involved three stages: (1) context assessment, (2) development/participation in implementation strategies, and (3) evaluation of intervention adherence. Results were variable. The context assessment (Stage 1) demonstrated the value of education, proactivity towards care and team structures. Strategies developed (Stage 2) included sepsis screening and response guide, education, team rounding, posters, champions, audit/feedback and knowledge brokering. In Stage 3, staff screened 92% patients (506/547) for sepsis at ≥60% of set times; only 33% (21/64) patients had a sepsis alert activated when needed. A similar proportion of patients who had alerts activated (n = 16, 76%) or not (n = 32, 74%) received at least one element of care. The use of implementation strategies resulted in adherence to some aspects of the intervention. Future research is needed to improve sepsis screening and alert activation and care in this setting.

Publication Type: Article
Additional Information: This is the peer reviewed version of the following article: Alberto, L., Marshall, A. P., Walker, R. M., Pálizas, F., & Aitken, L. M. (2021). Improving sepsis screening and care in a developing nation health setting: A description of implementation. Nursing & Health Sciences, 23( 4), 936– 947., which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
Publisher Keywords: Implementation strategies, sepsis screening, alert, care, hospital wards, developing nation
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RC Internal medicine
Departments: School of Health & Psychological Sciences
SWORD Depositor:
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