City Research Online

Ethics of ECPR research

Suverein, M. M., Shaw, D., Lorusso, R. , Delnoij, T. S. R., Essers, B., Weerwind, P. W., Townend, D. ORCID: 0000-0002-2409-0288, van de Poll, M. C. G. & Maessen, J. G. (2021). Ethics of ECPR research. Resuscitation, 169, pp. 136-142. doi: 10.1016/j.resuscitation.2021.08.007


The design of emergency medicine trials can raise several ethical concerns - risks may be greater, and randomisation may have to occur before consent. Research in emergency medicine is thus an illuminating context to explore the interplay between risk and randomisation, and the consequences for consent. Using a currently running trial, we describe possible concerns, considerations, and solutions to reconcile the conflicting interests of scientific inquiry, ethical principles, and clinical reality in emergency medicine research.

Publication Type: Article
Additional Information: 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license ( licenses/by/4.0/).
Publisher Keywords: Extracorporeal cardiopulmonary resuscitation, Out-of-hospital cardiac arrest, Refractory cardiac arrest, Informed consent, Ethical issues
Subjects: B Philosophy. Psychology. Religion > BJ Ethics
R Medicine > R Medicine (General)
Departments: The City Law School > Academic Programmes
SWORD Depositor:
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