City Research Online

Head Phantom Optical Properties Validation for Near-Infrared Measurements: A Comparison with Animal Tissue

Roldan, M. & Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2022). Head Phantom Optical Properties Validation for Near-Infrared Measurements: A Comparison with Animal Tissue. 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2022, pp. 641-644. ISSN 2375-7477 doi: 10.1109/EMBC48229.2022.9871103


The interest in optical healthcare technologies has increased significantly over the recent years. The innovation of new optical technologies such as Near Infrared Spectroscopy (NIRS), used for the monitoring of brain perfusion, demands a comprehensive understanding and knowledge of the light tissue interaction. Phantoms can provide a rigorous, reproducible and convenient approach for evaluating an optical sensor's performance. However, up to date literature does not provide a detailed description of a complete head model that involves the human anatomy, physiological changes, and the tissue optical properties. The latter is key for the design, development and testing of optical sensors, such as NIRS technologies. This paper compared the optical properties of the materials chosen to build a head phantom, against the optical properties of real brain and skull tissues extracted from animal models. The spectra of a silicone brain and resin skull samples were compared with the spectra of the respective tissues extracted from pigs and mice. The results of this study demonstrated that both phantom materials have similar optical properties to mice and pigs' tissues. The morphology of the phantom's spectra were very similar to the respective animal tissue comparator.

Publication Type: Conference or Workshop Item (Paper)
Additional Information: © 2022 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works
Publisher Keywords: Animals; Brain; Head; Humans; Mice; Phantoms, Imaging; Skull; Spectroscopy, Near-Infrared; Swine
Subjects: R Medicine > R Medicine (General)
T Technology > T Technology (General)
Departments: School of Science & Technology > Engineering
[thumbnail of EMBC_2022_Maria.pdf]
Text - Accepted Version
Download (308kB) | Preview


Add to AnyAdd to TwitterAdd to FacebookAdd to LinkedinAdd to PinterestAdd to Email


Downloads per month over past year

View more statistics

Actions (login required)

Admin Login Admin Login