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Optical Techniques for Blood and Tissue Oxygenation

Kyriacou, P. ORCID: 0000-0002-2868-485X, Budidha, K. ORCID: 0000-0002-6329-8399 & Abay, T. Y. (2019). Optical Techniques for Blood and Tissue Oxygenation. In: Narayan, R. (Ed.), Encyclopedia of Biomedical Engineering. (pp. 461-472). Elsevier. doi: 10.1016/b978-0-12-801238-3.10886-4


Throughout human history, light has played an important role in medicine. New optical techniques, many involving light emitting diodes, lasers, and fiber optics, are revolutionizing the field of diagnostic monitoring and therapy. Although at an adolescent stage, the power and potential of optical techniques, especially in monitoring blood and tissue oxygenation, has been well recognized, but is still rapidly developing. This review will cover various optical techniques currently used in the in vivo measurement of blood and tissue oxygenation, both in clinical and research settings. These include some well-established techniques such as pulse oximetry, fiber optic venous oximetry, and near-infrared spectroscopy, as well as other techniques that are not yet widely used such as white light spectrophotometry and fluorescence quenching. The review will describe the principles and applications of these techniques, in an attempt to illustrate their capabilities and limitations in measuring oxygenation in blood and tissues.

Publication Type: Book Section
Additional Information: Oxygenation, Haemoglobin, Pulse Oximetry, Near Infrared Spectroscopy, Reflectance Spectrophotometry, White light, Fluorescence, Phosphorescence, Photoplethysmography
Subjects: R Medicine > RC Internal medicine
T Technology > T Technology (General)
Departments: School of Science & Technology
School of Science & Technology > Engineering
School of Science & Technology > Mathematics
SWORD Depositor:
[thumbnail of Optical techniques for blood and tissue oxygenation.pdf] Text - Accepted Version
This document is not freely accessible due to copyright restrictions.


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