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Semi-Automatic Lymph Node Segmentation in LN-MRI

Unal, G. B., Slabaugh, G. G., Ess, A. , Yezzi, A. J., Fang, T., Tyan, J., Requardt, M., Krieg, R., Seethamraju, R., Harisinghani, M. & Weissleder, R. (2006). Semi-Automatic Lymph Node Segmentation in LN-MRI. Paper presented at the 2006 IEEE International Conference on Image Processing,, 08-10-2006 - 11-10-2006, Atlanta, USA. doi: 10.1109/ICIP.2006.312366


Accurate staging of nodal cancer still relies on surgical exploration because many primary malignancies spread via lymphatic dissemination. The purpose of this study was to utilize nanoparticle-enhanced lymphotropic magnetic resonance imaging (LN-MRI) to explore semi-automated noninvasive nodal cancer staging. We present a joint image segmentation and registration approach, which makes use of the problem specific information to increase the robustness of the algorithm to noise and weak contrast often observed in medical imaging applications. The effectiveness of the approach is demonstrated with a given lymph node segmentation problem in post-contrast pelvic MRI sequences.

Publication Type: Conference or Workshop Item (Paper)
Additional Information: © 2006 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Publisher Keywords: biomedical image processing, image segmentation, biomedical magnetic resonance imaging, medical diagnosis
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
R Medicine > RC Internal medicine
Departments: School of Science & Technology > Computer Science
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