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Shape-Driven Segmentation of the Arterial Wall in Intravascular Ultrasound Images

Unal, G. B., Bucher, S., Carlier, S. G., Slabaugh, G. G., Fang, T. and Tanaka, K. (2008). Shape-Driven Segmentation of the Arterial Wall in Intravascular Ultrasound Images. IEEE Transactions on Information Technology in Biomedicine, 12(3), pp. 335-347. doi: 10.1109/TITB.2008.920620


Segmentation of arterial wall boundaries from intravascular images is an important problem for many applications in the study of plaque characteristics, mechanical properties of the arterial wall, its 3-D reconstruction, and its measurements such as lumen size, lumen radius, and wall radius. We present a shape-driven approach to segmentation of the arterial wall from intravascular ultrasound images in the rectangular domain. In a properly built shape space using training data, we constrain the lumen and media-adventitia contours to a smooth, closed geometry, which increases the segmentation quality without any tradeoff with a regularizer term. In addition to a shape prior, we utilize an intensity prior through a nonparametric probability-density-based image energy, with global image measurements rather than pointwise measurements used in previous methods. Furthermore, a detection step is included to address the challenges introduced to the segmentation process by side branches and calcifications. All these features greatly enhance our segmentation method. The tests of our algorithm on a large dataset demonstrate the effectiveness of our approach.

Publication Type: Article
Additional Information: © 2008 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Publisher Keywords: intravascular ultrasound, arterial wall segmentation, lumen segmentation, media adventitia segmentation, calcification detection, side branch detection, shape prior, intensity prior, model-based segmentation
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
R Medicine > RC Internal medicine
Departments: School of Mathematics, Computer Science & Engineering > Computer Science
Date available in CRO: 23 Jan 2015 14:52
Date deposited: 29 July 2017
Date of first online publication: 2008
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