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Walsh, T. S., Parker, R. A., Aitken, L. M. ORCID: 0000-0001-5722-9090 , McKenzie, C. A., Emerson, L. ORCID: 0000-0002-4250-5758, Boyd, J., Macdonald, A., Beveridge, G., Giddings, A., Hope, D., Irvine, S., Tuck, S., Lone, N. I., Kydonaki, K., Norrie, J., Brealey, D., Antcliffe, D., Reay, M., Williams, A., Bewley, J., Creagh-Brown, B., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C., Perkins, G. D., Reade, M. C., Blackwood, B., MacLullich, A., Glen, R., Page, V. J., Weir, C. J., Pattison, N., Williams, B., Rose, L., Mouncey, P., Prowle, J., Wellsted, D., Walsh, T., Brett, S., Charles, H., Weir, C., Norrie, J., Bion, J., McLennan, G., Stevenson, M., Nichol, A., Walsh, T., Amamio, M., Barclay, L., Birch, S., Briton, K., Clark, S., Crossan, J., Doverman, K., Hope, D., Macdonald, L., McCulloch, C., Rae, N., Simpson, S., Singleton, J., Wishart, M., Thompson, R., Aitken, N., Fairlie, R., Salim, N., Talbot, S., Ackroyd, S., Alicino, V., Allan, E., Anderson, T., Andrew, R., Baigey, A., Baillie, K., Barnetson, C., Begbie, R., Biggers, R., Blaney, M., Broom, R., Birrell, D., Calkin, W., Chuavilong, K., Cowden, R., Cox, T., Darjee, C., Davies, S., Docherty, A., Dornan, L., Dunn, M., Edwardson, S., Gillespie, R., Greenwood, J., Griffith, D., Hay, A., Hu, A., Hunter, A., Jones, K., Jordan, H., Joseph, A., Kefala, K., Kelly, S., Kemp, L., Kubanova, B., Leng, V., Livesey, J., Lone, N., Lyon, J., Mansfield, O., McAvoy, D., McClatchey, A., Miller, J., Mirchandani, A., Moffitt, P., Morrison, S., Muir, A., Nunn, K., Ochiltree, J., Ogden, E., Parks, M., Pass, M., Penrose, R., Putnam, H., Quinn, T., Rhodes, J., Rollings, A., Ross, S., Shackleton, R., Shankar, M., Sharma, S., Slessor, I., Slevin, Z., Stickle, D., Symons, L., Walker, F., Walls, L., Whiteford, I., Yong, S. Y., Young, N., Rooney, K., Kinsella, M., Digby, B., Brett, M., McConnell, P., Henderson, M., Sundaram, R., Gemmell, L., Christie, F., Henderson, P., MacGregor, F., Henderson, S., Rodden, N., Fallon, K., Abel, L., McLaren, B., Hughes, E., McGlynn, D., Thomson, N., Walker, L., Currie, S., Parker, N., Gillan, D., Brohi, F., Purvis, S., Clark, M., Race, P., Williams, L., Shahin, A., Nworah, E., Gui, J., Cheng, L-C., Stewart, K., Cusack, R., Tomlin, M., Bolger, C., Burnish, R., Jackson, S., Baker, A., Biss, J., Salmon, K., Carter, M., McKenzie, C., Elsheikh, R., Harrison, M. A., Thomas, C., Ward, J., Cumpstey, A., Dushianthan, A., Kemp, I., Page, V., Zhao, X., Nordin, N., Hegazy, A., Hoxha, E., Hardaker, O., Ede, C., Kotrikova, N., Devaraja, A., Stambach, T., Mukherjee, P., Guanco, M. L., Wise, M. P., Cole, J., Hill, H., Brooks, J., Davies, M., Davies, R., Thomas, E., Williams, A., Lodhi, L., Morgan, M. P. G., Ridler, S., Smith, C., Faulkner, M., Ivison, A., McKay, L., Jeffrey, H., Price, J., Slater, L., Davies, A., Hughes, E., Thomas, M., Janssen, D., Thomas, I., Crewdson, K., Newell, C., Hirst, R., West, S., Skorko, A., Gendall, E., Worner, R., Faulkner, B., Borislavova, B., Hayes, K., Parsons, A., Goff, E., Sowersby, J., Wood, A., Oglesby, K., Sanusi, I., Pope, C., Baird, A., Blackmore, H., Healey, R., Hopkins, P., Corcoran, E., Selman, G., Finney, C., Pappa, E., Smith, J., Clarey, E., Cockrell, M., Saha, S., Noble, H., O’Reilly, K., Depante, M., Broderick, A., Axalan, M. A., Vergara, B., Mehta, R., Reschrieter, H., Patch, S., Camsooksai, J., Jenkins, S., Pomichowska, M., Power, K., Briggs, S., Woodward, E., Loew, C., Bromilow, J., Keegan, J., Taylor, M., Langridge, E., Kulandhaisamy, D., Savage, S., de’Ath, Y., Humphrey, C., Roffe, S., Bayliss, M., Bartlett, L., Gordon-Williams, R., Tatham, K., Smith, S., Noris, I., Tahir, S., Yates, E., Patel, S., Westerman, T., Bakare, S., Furness, H., Hunt, E., Zadeh, R. S., Khan, M., Sherwood, W., Addari, C., Manex, R., Whitehead, N., Wilson, F., Edwards, L., Nalk, K., Biddle, S., Lant, S., Holden, F., Voralia, S., Ocean, N., Sahni, A., Srilastava, P., Iqbal, S., Tana, S., Raman, V. V., Webb, Z., Parker, L., Dela Rosa, A., Kadr, M., Harvey, E., Howle, R., Husain, A., Morley, O., Loftus, S., Hutchinson, J., Jhanji, S., Black, E., Parkinson, D., Raobaikady, R., Borthwick, M., James, C., Polley, G., Davidson, N., Beer, S., Hutton, P., Bashyal, A., Wilson, J., Mathew, S., Ryu, J., Cupitt, J., Hardy, G., Benham, L., Downes, R., Flint, N., Little, M., Pochiraju, R., Andreou, P., Hales, D., Hailstone, J., Mathews, M., Huntley, M., Stephenson, L., Hussey, J., Tan, H-E., Holbrook, S., Kemp, H., Earl, D., Innes, R., Plumb, B., Doble, P., Purnell, R., Thomas, A., Noor, M. H., Khaliq, W., Jennings, M., Rose, B. O., Reece-Anthony, R., Khatun, S., Dickinson, S., Clarke, J., Cox, C., Longley, A., Ali, T., Gurung, B., Moubarak, M., Williams, A., Ball, J., Leaver, S., Farnell-Ward, S., Thanasi, M., Dangol, S., Ventura, V., Valcher, M., Sicat, C., Yun, N., Kanu, R., Cordoba, M. M., Trinh, H., Lloyd, K., Saluzzio, R. P., Ding, L., Farrah, H., Fernandes, E., Nutt, C., Silversides, J., McAuley, D., McGuigan, P., Major, E., Lonsdale, E., Fundano, N., Ward, K., Turley, C., O’Neill, A., Finn, S., Green, J., Collins, E., McAuley, J., Mills, J., Wright, C., Growcott, M., McCullagh, I., Wright, S., Clement, I., Shelton, J., Faulds, M., Hellyer, T., Morton, H., Pollard, C., White, C., Dunn, L., Calder, V., Taylor, S., Garcia, P., Brown, B., Savage, J., Babio-Galan, M., Webster, K., Wilkinson, T., Gulati, A., Shrestha, T., Hays, C., Butler, L., Simoes, F., McNeil, M., Storey, I., Whiteley, S., Wilby, E., Trott, S., Watts, S., Mathew, S., Salada, S., Neep, A., Youngs, N., Howcroft, C., Powell, M., Adlam, M., Paramasivam, E., Friar, Z., Antcliffe, D., Gordon, A., Banach, D., Rojo, R., Arias, S. S., Fernandez de Pinedo Artaraz, Z., Coghlan, P., Mohammed, A., Jepson, E., Wong, J., Gurung, A. T., O’Dwyer, C., Perez Guillotin, S., Templeton, M., Hanison, J., Bannard-Smith, J., Conway, D., Abbas, S., Aly, M., Benington, S., Eng Hean, T., Hayley, D., McGuckin, E., Martin, A., Morris, T., Musselbrook, W., Narayan, B., Wright, T., Wheeler, C., Barker, M., Clark, R., Connaughton, E., Jama, R., Paripoorani, D., Quayle, R., Sukumaran, A., Taylor, C., Balmer, M., Lingeswaran, S., Edmunds, L., Wylie, K., Owen, A., Perkins, G., Munnelly, S., Park, D., Gresty, J., Reeves, E., Maliaykal, C., Melody, T., Preller, J., Polgarova, P., Bravoelvira, C., Teixeira, S., Varley, J., Hajela, S. S., Elston, K., Campbell, S., Keil, M., Elbehery, M., Marshall, J., Stevenson, S., Conway Morris, A., Gogineni Venkateskara, P., Reay, M., Reid, K., Brown, R., Amareihe, C., Yates, E., Luen Goh, J., Jones, E., Mughal, A., Brealey, D., MacCallum, N., Clark, S., Smyth, D., Bercades, G., Hass, I., Martir, G., Reyes, A., Martinez, M. A. Z., Gallagher, L., Yee Chung, C., Sanders, G., Chawla, V., Maheshwari, N., Glazebrook, T., Angel, H., Squires, R., Dolan, H., Donnelly, C., Mires, L., Musalagani, R., Williams, S., Heij, R., Young, P., Blunt, M., Wijewardena, G., Gibson, J., Joshy, A. M., Bewley, J., Rooney, K., Sweet, K., Wright, K., Grimmer, L., Webster, D., Bazan Lacerot, C., Shiel, R., Hernandez Morano, E. M., Coleman, C., Daniel, E., Komolafe, O., Bonnici, J., Pipira, L., Johnson, R., Chillingworth, A., Liang, Y-H., Efford, G., Kolovou, A., Davies, G., Garland, Z., Gumbrill, B., Collin, I., Gibbins, M., Brougham, T., Harvey, D., Phipps, W., Harrold, K., Plummer, N., Lowe, B., James, P., Ahmed, S., Ghosh, R., Mohamed, O., Santra, T., Shilston, J., Russell, A., Patel, V., Topiwala, U., Bello, H., Sampson, J., Ryan, L., Peters, C., Meredith, M., Conner (now Hughes), L., Morris, L., Clark, A., Baddeley, A., Mcloughlin, L., Walton, C., Joseph, T., Thomas, A., Lubbock, S., Ford, D., McCoy, A., N’Dungu, T., Welters, I., Sankar, V., Waite, A., Johnston, B., Shaw, D., Waugh, V., Williams, K., Lopez Martinez, M., Norris, M., Carlota Mahiya, M. A., Fernandez Roman, J., Yuan, J-X., Manes, S., Lythgoe, C., Almafreji, I., Colfar, J., Medhurst, L., Beresford, S., Farina, S., Imam, L., Ali, S., Thomas, Z., Bold, F., Hodson, K., Morenikeji, A., Watkin, D., Szakmany, T., Cardwell, A., Frawley, A., Ostermann, M., Radcliffe, G., Barrett, N., Sparkes, S., Woodman-Bailey, A., Kosifidou, E., Bociek, A., Hendrie, E., Lim, R., D’Amato, F., Fordyce, S., Cendreda, B., Morera Vas, K., Pan, J., Meddings, C., Milic, V., Barker, M., Owusu-Afriyie, J., Engelhard, C., Sim, M., Appleton, R., Ralston, M., Arnott, A., Orlikowska, I., Kennedy-Hay, S., Murray, C., Devine, M., Headley, P., McCaffrey, J., Donnelly, D., Young, R., Hagan, S., Adell, V., Murphy, E., Quek, J., Wilson, S., Jardine, C., Forrest, M., Collins, E., Ibrahim, M., Wheeley, M., Kodous, M., Blake, M., Lacey, V., Eager, M., Jootun, R. & Birch, J.view all authors (2025). Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients. JAMA, 334(1), doi: 10.1001/jama.2025.7200

Aitken, L. ORCID: 0000-0001-5722-9090, Emerson, L. M., Kydonaki, K. , Blackwood, B., Creagh-Brown, B., Lone, N., McKenzie, C., Parker, R., Reade, M. C., Weir, C. J., Wise, M. P. & Walsh, T. S.view all authors (2025). Process Evaluation of the A2B randomised controlled trial: an exploration of the factors influencing successful implementation, delivery, and outcomes in an intensive care sedation study. Health Technology Assessment,

Aitken, L. M. ORCID: 0000-0001-5722-9090, Emerson, L. M. ORCID: 0000-0002-4250-5758, Kydonaki, K. , Blackwood, B., Creagh-Brown, B., Lone, N. I., McKenzie, C. A., Reade, M. C., Weir, C. J., Wise, M. P. & Walsh, T. S.view all authors (2024). Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial. BMJ Open, 14(4), article number e081637. doi: 10.1136/bmjopen-2023-081637

Walsh, T. S., Aitken, L. M. ORCID: 0000-0001-5722-9090, McKenzie, C. A. , Boyd, J., Macdonald, A., Giddings, A., Hope, D., Norrie, J., Weir, C., Parker, R. A., Lone, N. I., Emerson, L. M. ORCID: 0000-0002-4250-5758, Kydonaki, K., Creagh-Brown, B., Morris, S., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C., Perkins, G., Reade, M., Blackwood, B., MacLullich, A., Glen, R. & Page, V. J.view all authors (2023). Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK. BMJ Open, 13(12), article number e078645. doi: 10.1136/bmjopen-2023-078645