Items where Author is "Walsh, T. S."
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Walsh, T. S., Parker, R. A., Aitken, L. 
ORCID: 0000-0001-5722-9090 , McKenzie, C. A., Glen, R. & Weir, C. J. (2025).
Relative and bedside nurse assessment of comfort and communication during propofol, dexmedetomidine, or clonidine-based sedation: pre-planned analysis within the A2B RCT.
Health Technology Assessment,
Walsh, T. S., Parker, R. A., Aitken, L. M. ORCID: 0000-0001-5722-9090 , McKenzie, C. A., Emerson, L. ORCID: 0000-0002-4250-5758, Boyd, J., Macdonald, A., Beveridge, G., Giddings, A., Hope, D., Irvine, S., Tuck, S., Lone, N. I., Kydonaki, K., Norrie, J., Brealey, D., Antcliffe, D., Reay, M., Williams, A., Bewley, J., Creagh-Brown, B., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C., Perkins, G. D., Reade, M. C., Blackwood, B., MacLullich, A., Glen, R., Page, V. J., Weir, C. J., Pattison, N., Williams, B., Rose, L., Mouncey, P., Prowle, J., Wellsted, D., Walsh, T., Brett, S., Charles, H., Weir, C., Norrie, J., Bion, J., McLennan, G., Stevenson, M., Nichol, A., Walsh, T., Amamio, M., Barclay, L., Birch, S., Briton, K., Clark, S., Crossan, J., Doverman, K., Hope, D., Macdonald, L., McCulloch, C., Rae, N., Simpson, S., Singleton, J., Wishart, M., Thompson, R., Aitken, N., Fairlie, R., Salim, N., Talbot, S., Ackroyd, S., Alicino, V., Allan, E., Anderson, T., Andrew, R., Baigey, A., Baillie, K., Barnetson, C., Begbie, R., Biggers, R., Blaney, M., Broom, R., Birrell, D., Calkin, W., Chuavilong, K., Cowden, R., Cox, T., Darjee, C., Davies, S., Docherty, A., Dornan, L., Dunn, M., Edwardson, S., Gillespie, R., Greenwood, J., Griffith, D., Hay, A., Hu, A., Hunter, A., Jones, K., Jordan, H., Joseph, A., Kefala, K., Kelly, S., Kemp, L., Kubanova, B., Leng, V., Livesey, J., Lone, N., Lyon, J., Mansfield, O., McAvoy, D., McClatchey, A., Miller, J., Mirchandani, A., Moffitt, P., Morrison, S., Muir, A., Nunn, K., Ochiltree, J., Ogden, E., Parks, M., Pass, M., Penrose, R., Putnam, H., Quinn, T., Rhodes, J., Rollings, A., Ross, S., Shackleton, R., Shankar, M., Sharma, S., Slessor, I., Slevin, Z., Stickle, D., Symons, L., Walker, F., Walls, L., Whiteford, I., Yong, S. Y., Young, N., Rooney, K., Kinsella, M., Digby, B., Brett, M., McConnell, P., Henderson, M., Sundaram, R., Gemmell, L., Christie, F., Henderson, P., MacGregor, F., Henderson, S., Rodden, N., Fallon, K., Abel, L., McLaren, B., Hughes, E., McGlynn, D., Thomson, N., Walker, L., Currie, S., Parker, N., Gillan, D., Brohi, F., Purvis, S., Clark, M., Race, P., Williams, L., Shahin, A., Nworah, E., Gui, J., Cheng, L-C., Stewart, K., Cusack, R., Tomlin, M., Bolger, C., Burnish, R., Jackson, S., Baker, A., Biss, J., Salmon, K., Carter, M., McKenzie, C., Elsheikh, R., Harrison, M. A., Thomas, C., Ward, J., Cumpstey, A., Dushianthan, A., Kemp, I., Page, V., Zhao, X., Nordin, N., Hegazy, A., Hoxha, E., Hardaker, O., Ede, C., Kotrikova, N., Devaraja, A., Stambach, T., Mukherjee, P., Guanco, M. L., Wise, M. P., Cole, J., Hill, H., Brooks, J., Davies, M., Davies, R., Thomas, E., Williams, A., Lodhi, L., Morgan, M. P. G., Ridler, S., Smith, C., Faulkner, M., Ivison, A., McKay, L., Jeffrey, H., Price, J., Slater, L., Davies, A., Hughes, E., Thomas, M., Janssen, D., Thomas, I., Crewdson, K., Newell, C., Hirst, R., West, S., Skorko, A., Gendall, E., Worner, R., Faulkner, B., Borislavova, B., Hayes, K., Parsons, A., Goff, E., Sowersby, J., Wood, A., Oglesby, K., Sanusi, I., Pope, C., Baird, A., Blackmore, H., Healey, R., Hopkins, P., Corcoran, E., Selman, G., Finney, C., Pappa, E., Smith, J., Clarey, E., Cockrell, M., Saha, S., Noble, H., O’Reilly, K., Depante, M., Broderick, A., Axalan, M. A., Vergara, B., Mehta, R., Reschrieter, H., Patch, S., Camsooksai, J., Jenkins, S., Pomichowska, M., Power, K., Briggs, S., Woodward, E., Loew, C., Bromilow, J., Keegan, J., Taylor, M., Langridge, E., Kulandhaisamy, D., Savage, S., de’Ath, Y., Humphrey, C., Roffe, S., Bayliss, M., Bartlett, L., Gordon-Williams, R., Tatham, K., Smith, S., Noris, I., Tahir, S., Yates, E., Patel, S., Westerman, T., Bakare, S., Furness, H., Hunt, E., Zadeh, R. S., Khan, M., Sherwood, W., Addari, C., Manex, R., Whitehead, N., Wilson, F., Edwards, L., Nalk, K., Biddle, S., Lant, S., Holden, F., Voralia, S., Ocean, N., Sahni, A., Srilastava, P., Iqbal, S., Tana, S., Raman, V. V., Webb, Z., Parker, L., Dela Rosa, A., Kadr, M., Harvey, E., Howle, R., Husain, A., Morley, O., Loftus, S., Hutchinson, J., Jhanji, S., Black, E., Parkinson, D., Raobaikady, R., Borthwick, M., James, C., Polley, G., Davidson, N., Beer, S., Hutton, P., Bashyal, A., Wilson, J., Mathew, S., Ryu, J., Cupitt, J., Hardy, G., Benham, L., Downes, R., Flint, N., Little, M., Pochiraju, R., Andreou, P., Hales, D., Hailstone, J., Mathews, M., Huntley, M., Stephenson, L., Hussey, J., Tan, H-E., Holbrook, S., Kemp, H., Earl, D., Innes, R., Plumb, B., Doble, P., Purnell, R., Thomas, A., Noor, M. H., Khaliq, W., Jennings, M., Rose, B. O., Reece-Anthony, R., Khatun, S., Dickinson, S., Clarke, J., Cox, C., Longley, A., Ali, T., Gurung, B., Moubarak, M., Williams, A., Ball, J., Leaver, S., Farnell-Ward, S., Thanasi, M., Dangol, S., Ventura, V., Valcher, M., Sicat, C., Yun, N., Kanu, R., Cordoba, M. M., Trinh, H., Lloyd, K., Saluzzio, R. P., Ding, L., Farrah, H., Fernandes, E., Nutt, C., Silversides, J., McAuley, D., McGuigan, P., Major, E., Lonsdale, E., Fundano, N., Ward, K., Turley, C., O’Neill, A., Finn, S., Green, J., Collins, E., McAuley, J., Mills, J., Wright, C., Growcott, M., McCullagh, I., Wright, S., Clement, I., Shelton, J., Faulds, M., Hellyer, T., Morton, H., Pollard, C., White, C., Dunn, L., Calder, V., Taylor, S., Garcia, P., Brown, B., Savage, J., Babio-Galan, M., Webster, K., Wilkinson, T., Gulati, A., Shrestha, T., Hays, C., Butler, L., Simoes, F., McNeil, M., Storey, I., Whiteley, S., Wilby, E., Trott, S., Watts, S., Mathew, S., Salada, S., Neep, A., Youngs, N., Howcroft, C., Powell, M., Adlam, M., Paramasivam, E., Friar, Z., Antcliffe, D., Gordon, A., Banach, D., Rojo, R., Arias, S. S., Fernandez de Pinedo Artaraz, Z., Coghlan, P., Mohammed, A., Jepson, E., Wong, J., Gurung, A. T., O’Dwyer, C., Perez Guillotin, S., Templeton, M., Hanison, J., Bannard-Smith, J., Conway, D., Abbas, S., Aly, M., Benington, S., Eng Hean, T., Hayley, D., McGuckin, E., Martin, A., Morris, T., Musselbrook, W., Narayan, B., Wright, T., Wheeler, C., Barker, M., Clark, R., Connaughton, E., Jama, R., Paripoorani, D., Quayle, R., Sukumaran, A., Taylor, C., Balmer, M., Lingeswaran, S., Edmunds, L., Wylie, K., Owen, A., Perkins, G., Munnelly, S., Park, D., Gresty, J., Reeves, E., Maliaykal, C., Melody, T., Preller, J., Polgarova, P., Bravoelvira, C., Teixeira, S., Varley, J., Hajela, S. S., Elston, K., Campbell, S., Keil, M., Elbehery, M., Marshall, J., Stevenson, S., Conway Morris, A., Gogineni Venkateskara, P., Reay, M., Reid, K., Brown, R., Amareihe, C., Yates, E., Luen Goh, J., Jones, E., Mughal, A., Brealey, D., MacCallum, N., Clark, S., Smyth, D., Bercades, G., Hass, I., Martir, G., Reyes, A., Martinez, M. A. Z., Gallagher, L., Yee Chung, C., Sanders, G., Chawla, V., Maheshwari, N., Glazebrook, T., Angel, H., Squires, R., Dolan, H., Donnelly, C., Mires, L., Musalagani, R., Williams, S., Heij, R., Young, P., Blunt, M., Wijewardena, G., Gibson, J., Joshy, A. M., Bewley, J., Rooney, K., Sweet, K., Wright, K., Grimmer, L., Webster, D., Bazan Lacerot, C., Shiel, R., Hernandez Morano, E. M., Coleman, C., Daniel, E., Komolafe, O., Bonnici, J., Pipira, L., Johnson, R., Chillingworth, A., Liang, Y-H., Efford, G., Kolovou, A., Davies, G., Garland, Z., Gumbrill, B., Collin, I., Gibbins, M., Brougham, T., Harvey, D., Phipps, W., Harrold, K., Plummer, N., Lowe, B., James, P., Ahmed, S., Ghosh, R., Mohamed, O., Santra, T., Shilston, J., Russell, A., Patel, V., Topiwala, U., Bello, H., Sampson, J., Ryan, L., Peters, C., Meredith, M., Conner (now Hughes), L., Morris, L., Clark, A., Baddeley, A., Mcloughlin, L., Walton, C., Joseph, T., Thomas, A., Lubbock, S., Ford, D., McCoy, A., N’Dungu, T., Welters, I., Sankar, V., Waite, A., Johnston, B., Shaw, D., Waugh, V., Williams, K., Lopez Martinez, M., Norris, M., Carlota Mahiya, M. A., Fernandez Roman, J., Yuan, J-X., Manes, S., Lythgoe, C., Almafreji, I., Colfar, J., Medhurst, L., Beresford, S., Farina, S., Imam, L., Ali, S., Thomas, Z., Bold, F., Hodson, K., Morenikeji, A., Watkin, D., Szakmany, T., Cardwell, A., Frawley, A., Ostermann, M., Radcliffe, G., Barrett, N., Sparkes, S., Woodman-Bailey, A., Kosifidou, E., Bociek, A., Hendrie, E., Lim, R., D’Amato, F., Fordyce, S., Cendreda, B., Morera Vas, K., Pan, J., Meddings, C., Milic, V., Barker, M., Owusu-Afriyie, J., Engelhard, C., Sim, M., Appleton, R., Ralston, M., Arnott, A., Orlikowska, I., Kennedy-Hay, S., Murray, C., Devine, M., Headley, P., McCaffrey, J., Donnelly, D., Young, R., Hagan, S., Adell, V., Murphy, E., Quek, J., Wilson, S., Jardine, C., Forrest, M., Collins, E., Ibrahim, M., Wheeley, M., Kodous, M., Blake, M., Lacey, V., Eager, M., Jootun, R. & Birch, J. (2025).
Dexmedetomidine- or Clonidine-Based Sedation Compared With Propofol in Critically Ill Patients.
JAMA, 334(1),
doi: 10.1001/jama.2025.7200
Aitken, L. ORCID: 0000-0001-5722-9090, Emerson, L. M., Kydonaki, K. , Blackwood, B., Creagh-Brown, B., Lone, N., McKenzie, C., Parker, R., Reade, M. C., Weir, C. J., Wise, M. P. & Walsh, T. S. (2025).
Process Evaluation of the A2B randomised controlled trial: an exploration of the factors influencing successful implementation, delivery, and outcomes in an intensive care sedation study.
Health Technology Assessment,
Aitken, L. M. ORCID: 0000-0001-5722-9090, Emerson, L. M. ORCID: 0000-0002-4250-5758, Kydonaki, K. , Blackwood, B., Creagh-Brown, B., Lone, N. I., McKenzie, C. A., Reade, M. C., Weir, C. J., Wise, M. P. & Walsh, T. S. (2024).
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B trial): protocol for a mixed-methods process evaluation of a randomised controlled trial.
BMJ Open, 14(4),
article number e081637.
doi: 10.1136/bmjopen-2023-081637
Walsh, T. S., Aitken, L. M. ORCID: 0000-0001-5722-9090, McKenzie, C. A. , Boyd, J., Macdonald, A., Giddings, A., Hope, D., Norrie, J., Weir, C., Parker, R. A., Lone, N. I., Emerson, L. M. ORCID: 0000-0002-4250-5758, Kydonaki, K., Creagh-Brown, B., Morris, S., McAuley, D. F., Dark, P., Wise, M. P., Gordon, A. C., Perkins, G., Reade, M., Blackwood, B., MacLullich, A., Glen, R. & Page, V. J. (2023).
Alpha 2 agonists for sedation to produce better outcomes from critical illness (A2B Trial): protocol for a multicentre phase 3 pragmatic clinical and cost-effectiveness randomised trial in the UK.
BMJ Open, 13(12),
article number e078645.
doi: 10.1136/bmjopen-2023-078645
Aitken, L. M. ORCID: 0000-0001-5722-9090, Kydonaki, K., Blackwood, B. , Trahair, L. G., Purssell, E. ORCID: 0000-0003-3748-0864, Sekhon, M. & Walsh, T. S. (2021).
Inconsistent relationship between depth of sedation and intensive care outcome: systematic review and meta-analysis.
Thorax, 76(11),
pp. 1089-1098.
doi: 10.1136/thoraxjnl-2020-216098
Hellyer, T. P., McAuley, D. F., Walsh, T. S. , Anderson, N. H., Conway Morris, A., Singh, S., Dark, P., Roy, A. I., Perkins, G. D., McMullan, R., Emerson, L. M. ORCID: 0000-0002-4250-5758, Blackwood, B., Wright, S. E., Kefala, K., O’Kane, C. M., Baudouin, S. V., Paterson, R. L., Rostron, A. J., Agus, A. M., Bannard-Smith, J., Robin, N. M., Welters, I. D., Bassford, C., Yates, B., Spencer, C., Laha, S. K., Hulme, J., Bonner, S., Linnett, V., Sonksen, J., Van Den Broeck, T., Boschman, G., Keenan, D. W. J., Scott, J., Allen, A. J., Phair, G., Parker, J., Bowett, S. A. & Simpson, A. J. (2020).
More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia.
Annals of Translational Medicine, 8(13),
article number 840.
doi: 10.21037/atm-20-3701
Hellyer, T. P., McAuley, D. F., Walsh, T. S. , Anderson, N., Conway Morris, A., Singh, S., Dark, P., Roy, A. I., Perkins, G. D., McMullan, R., Emerson, L. M. ORCID: 0000-0002-4250-5758, Blackwood, B., Wright, S. E., Kefala, K., O'Kane, C. M., Baudouin, S. V., Paterson, R. L., Rostron, A. J., Agus, A., Bannard-Smith, J., Robin, N. M., Welters, I. D., Bassford, C., Yates, B., Spencer, C., Laha, S. K., Hulme, J., Bonner, S., Linnett, V., Sonksen, J., Van Den Broeck, T., Boschman, G., Keenan, D. W. J., Scott, J., Allen, A. J., Phair, G., Parker, J., Bowett, S. A. & Simpson, A. J. (2020).
Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation.
The Lancet Respiratory Medicine, 8(2),
pp. 182-191.
doi: 10.1016/s2213-2600(19)30367-4
Hellyer, T. P., Anderson, N. H., Parker, J. , Dark, P., Van Den Broeck, T., Singh, S., McMullan, R., Agus, A. M., Emerson, L. M. ORCID: 0000-0002-4250-5758, Blackwood, B., Gossain, S., Walsh, T. S., Perkins, G. D., Morris, A. C., McAuley, D. F. & Simpson, A. J. (2016).
Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial.
Trials, 17(1),
article number 318.
doi: 10.1186/s13063-016-1442-x
Hellyer, T. P., Anderson, N. H., Parker, J. , Dark, P., Van Den Broeck, T., Singh, S., McMullan, R., Agus, A. M., Emerson, L. M. ORCID: 0000-0002-4250-5758, Blackwood, B., Gossain, S., Walsh, T. S., Perkins, G. D., Morris, A. C., McAuley, D. F. & Simpson, A. J. (2016).
Erratum to: ‘Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial’.
Trials, 17(1),
article number 465.
doi: 10.1186/s13063-016-1594-8