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Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study

Harding-Esch, E., Jofre-Bonet, M., Dhanjal, J. K. , Burr, S., Edwards, T., Holland, M., Sillah, A., West, S., Lietman, T., Keenan, J., Mabey, D. & Bailey, R. (2015). Costs of Testing for Ocular Chlamydia trachomatis Infection Compared to Mass Drug Administration for Trachoma in The Gambia: Application of Results from the PRET Study. PLoS Neglected Tropical Diseases, 9(4), article number e0003670. doi: 10.1371/journal.pntd.0003670

Abstract

Mass drug administration (MDA) treatment of active trachoma with antibiotic is recommended to be initiated in any district where the prevalence of trachoma inflammation, follicular (TF) is ≥10% in children aged 1-9 years, and then to continue for at least three annual rounds before resurvey. In The Gambia the PRET study found that discontinuing MDA based on testing a sample of children for ocular Chlamydia trachomatis(Ct) infection after one MDA round had similar effects to continuing MDA for three rounds. Moreover, one round of MDA reduced disease below the 5% TF threshold. We compared the costs of examining a sample of children for TF, and of testing them for Ct, with those of MDA rounds.

Publication Type: Article
Publisher Keywords: The Gambia, Trachoma, Chlamydia trachomatis, Cost, Treatment
Subjects: H Social Sciences > HB Economic Theory
R Medicine > RC Internal medicine
Departments: School of Policy & Global Affairs > Economics
SWORD Depositor:
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