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Possible Early Generation of Physiological Helical Flow Could Benefit the Triflo Trileaflet Heart Valve Prosthesis Compared to Bileaflet Valves

Bruecker, C. ORCID: 0000-0001-5834-3020 and Li, Q. (2020). Possible Early Generation of Physiological Helical Flow Could Benefit the Triflo Trileaflet Heart Valve Prosthesis Compared to Bileaflet Valves. Bioengineering, 7(4), 158.. doi: 10.3390/bioengineering7040158

Abstract

Background—Physiological helical flow in the ascending aorta has been well documented in the last two decades, accompanied by discussions on possible physiological benefits of such axial swirl. Recent 4D-MRI studies on healthy volunteers have found indications of early generation of helical flow, early in the systole and close to the valve plane. Objectives—Firstly, the aim of the study is to investigate the hypothesis of premature swirl existence in the ventricular outflow tract leading to helical flow in the valve plane, and second to investigate the possible impact of two different mechanical valve designs on the preservation of this early helical flow and its subsequent hemodynamic consequences. Methods—We use a pulse duplicator with an aortic arch and High-Speed Particle Image Velocimetry to document the flow evolution in the systolic cycle. The pulse-duplicator is modified with a swirl-generating insert to generate early helical flow in the valve plane. Special focus is paid to the interaction of such helical flow with different designs of mechanical prosthetic heart valves, comparing a classical bileaflet mechanical heart valve, the St. Jude Medical Regent valve (SJM Regent BMHV), with the Triflo trileaflet mechanical heart valve T2B version (Triflo TMHV). Results—When the swirl-generator is inserted, a vortex is generated in the core flow, demonstrating early helical flow in the valve plane, similar to the observations reported in the recent 4D-MRI study taken for comparison. For the Triflo trileaflet valve, the early helical flow is not obstructed in the central orifice, similar as in the case of the natural valve. Conservation of angular momentum leads to radial expansion of the core flow and flattening of the axial flow profile downstream in the arch. Furthermore, the early helical flow helps to overcome separation at the outer and inner curvature. In contrast, the two parallel leaflets for the bileaflet valve impose a flow straightener effect, annihilating the angular momentum, which has a negative impact on kinetic energy of the flow. Conclusion—The results imply better hemodynamics for the Triflo trileaflet valve based on hydrodynamic arguments under the discussed hypothesis. In addition, it makes the Triflo valve a better candidate for valve replacements in patients with a pathological generation of nonaxial velocity in the ventricle outflow tract.

Publication Type: Article
Additional Information: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Publisher Keywords: physiological helical flow; mechanical heart valve prostheses; aorta; PIV; trileaflet
Subjects: Q Science > QC Physics
Q Science > QM Human anatomy
R Medicine > RC Internal medicine
T Technology > TL Motor vehicles. Aeronautics. Astronautics
Departments: School of Mathematics, Computer Science & Engineering > Engineering > Mechanical Engineering & Aeronautics
Date Deposited: 09 Dec 2020 15:03
URI: https://openaccess.city.ac.uk/id/eprint/25382
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