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Trail-Traced Threshold Test (T4) with a Weighted Binomial Distribution for a Psychophysical Test

Gong, Y., Zhu, H., Miranda, M. A., Crabb, D. P. ORCID: 0000-0001-8754-3902, Yang, H., Bi, W. and Garway-Heath, D. F. (2021). Trail-Traced Threshold Test (T4) with a Weighted Binomial Distribution for a Psychophysical Test. IEEE Journal of Biomedical and Health Informatics, 25(7), pp. 2787-2800. doi: 10.1109/JBHI.2021.3057437

Abstract

Clinical visual field testing is performed with commercial perimetric devices and employs psychophysical techniques to obtain thresholds of the differential light sensitivity (DLS) at multiple retinal locations. Current thresholding algorithms are relatively inefficient and tough to get satisfied test accuracy, stability concurrently. Thus, we propose a novel Bayesian perimetric threshold method called the Trail-Traced Threshold Test (T4), which can better address the dependence of the initial threshold estimation and achieve significant improvement in the test accuracy and variability while also decreasing the number of presentations compared with Zippy Estimation by Sequential Testing (ZEST) and FT. This study compares T4 with ZEST and FT regarding presentation number, mean absolute difference (MAD between the real Visual field result and the simulate result), and measurement variability. T4 uses the complete response sequence with the spatially weighted neighbor responses to achieve better accuracy and precision than ZEST and FT and with significantly fewer stimulus presentations. T4 is also more robust to inaccurate initial threshold estimation than other methods, which is an advantage in subjective methods, such as in clinical perimetry. This method also has the potential for use in other psychophysical tests.

Publication Type: Article
Additional Information: © 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Publisher Keywords: Bayesian, perimetric threshold test, spatial weight, standard automated perimetry, visual field
Subjects: B Philosophy. Psychology. Religion > BF Psychology
H Social Sciences > HA Statistics
R Medicine > RE Ophthalmology
Departments: School of Health Sciences > Optometry & Visual Science
Date available in CRO: 14 Jun 2021 10:51
Date deposited: 14 June 2021
Date of acceptance: 28 January 2021
Date of first online publication: 5 February 2021
URI: https://openaccess.city.ac.uk/id/eprint/26248
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