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Developing technologies to assess vascular ageing: a roadmap from VascAgeNet

Zanelli, S. ORCID: 0000-0002-8020-8375, Agnoletti, D., Alastruey, J. , Allen, J. ORCID: 0000-0002-7263-0533, Bianchini, E., Bikia, V., Boutouyrie, P., Bruno, R. M., Climie, R., Djamaleddine, D., Gkaliagkousi, E., Giudici, A. ORCID: 0000-0002-8288-3980, Gopcevic, K., Grillo, A., Guala, A., Hametner, B. ORCID: 0000-0003-2048-1019, Joseph, J., Karimpour, P., Kodithuwakku, V., Kyriacou, P. A. ORCID: 0000-0002-2868-485X, Lazaridis, A., Lonnebakken, M. T., Martina, M. R. ORCID: 0000-0003-2489-8639, Mayer, C. C. ORCID: 0000-0002-5612-5481, Nabeel, P. M., Navickas, P., Nemcsik, J., Orter, S. ORCID: 0000-0001-9258-6069, Park, C., Pereira, T., Pucci, G., Amado Rey, A. B., Salvi, P., Gonçalves Seabra, A. C., Seeland, U., van Sloten, T., Spronck, B. ORCID: 0000-0003-1076-1922, Stansby, G., Steens, I., Stieglitz, T., Tan, I., Veerasingam, D., Wassertheurer, S., Weber, T., Westerhof, B. E. & Charlton, P. H. ORCID: 0000-0003-3836-8655 (2024). Developing technologies to assess vascular ageing: a roadmap from VascAgeNet. Physiological Measurement, doi: 10.1088/1361-6579/ad548e

Abstract

Vascular ageing is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular risk, with potential applications in disease diagnosis and prognosis, and for guiding treatments. However, vascular ageing is not yet routinely assessed in clinical practice. A key step towards this is the development of technologies to assess vascular ageing. In this Roadmap, experts discuss several aspects of this process, including: measurement technologies; the development pipeline; clinical applications; and future research directions. The Roadmap summarises the state of the art, outlines the major challenges to overcome, and identifies potential future research directions to address these challenges.

Publication Type: Article
Additional Information: As the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 4.0 licence, this Accepted Manuscript is available for reuse under a CC BY 4.0 licence immediately.
Publisher Keywords: arterial stiffness, arteriosclerosis, atherosclerosis, blood pressure, cardiovascular, prevention, pulse wave velocity, 0903 Biomedical Engineering, 0906 Electrical and Electronic Engineering, 1116 Medical Physiology, Biomedical Engineering, 3208 Medical physiology, 4003 Biomedical engineering
Subjects: R Medicine > RC Internal medicine
Departments: School of Science & Technology
School of Science & Technology > Engineering
SWORD Depositor:
[thumbnail of roadmap from VascAgeNet.pdf]
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