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Monte Carlo Simulation of the Effect of Melanin Concentration on Light–Tissue Interactions in Reflectance Pulse Oximetry

Al-Halawani, R. ORCID: 0000-0002-6193-921X, Qassem, M. ORCID: 0000-0003-0730-3189 & Kyriacou, P. A. ORCID: 0000-0002-2868-485X (2025). Monte Carlo Simulation of the Effect of Melanin Concentration on Light–Tissue Interactions in Reflectance Pulse Oximetry. Sensors, 25(2), article number 559. doi: 10.3390/s25020559

Abstract

Over the past ten years, there has been an increasing demand for reliable consumer wearables as users are inclined to monitor their health and fitness metrics in real-time, especially since the COVID-19 pandemic. Reflectance pulse oximeters in fitness trackers and smartwatches provide convenient, non-invasive SpO2 measurements but face challenges in achieving medical-grade accuracy, particularly due to difficulties in capturing physiological signals, which may be affected by skin pigmentation. Hence, this study sets out to investigate the influence of skin pigmentation, particularly in individuals with darker skin, on the accuracy and reliability of SpO2 measurement in consumer wearables that utilise reflectance pulse oximeters. A Monte Carlo model is developed to assess the effect on simulated reflectance pulse oximetry measurements across light, moderate, and dark skin types for oxygen saturation levels between 70 and 100%. The results indicate that a one-algorithm-fits-all calibration approach may be insufficient, and root mean square errors (RMSEs) of at least 0.3956%, 0.9132%, and 8.4111% for light, moderate, and dark skin are observed when compared to transmittance calibration algorithms. Further research is required to validate these findings and improve the performance of reflectance pulse oximeters in real-world applications, particularly in the context of consumer wearables.

Publication Type: Article
Additional Information: © 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license(https://creativecommons.org/licenses/by/4.0/).
Publisher Keywords: Monte Carlo simulation; photoplethysmography; skin pigmentation; oxygen saturation; pulse oximetry
Subjects: R Medicine > RC Internal medicine
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Departments: School of Science & Technology
School of Science & Technology > Engineering
SWORD Depositor:
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