City Research Online

Abstract

Cooperation arises in nature at every scale, from within cells to entire ecosystems. Public goods games (PGGs) are used to represent scenarios characterised by the conflict/dilemma between choosing cooperation as a socially optimal strategy and defection as an individually optimal strategy. Evolutionary game theory is often used to analyse the dynamics of behaviour emergence in this context. Here, we focus on PGGs arising in the disease modelling of cancer evolution and the spread of infectious diseases. We use these two systems as case studies for the development of the theory and applications of PGGs, which we succinctly review. We also posit that applications of evolutionary game theory to decision-making in cancer, such as interactions between a clinician and a tumour, can learn from the PGGs studied in epidemiology, where cooperative behaviours such as quarantine and vaccination compliance have been more thoroughly investigated. Furthermore, instances of cellular-level cooperation observed in cancers point to a corresponding area of potential interest for modellers of other diseases, be they viral, bacterial or otherwise. We aim to demonstrate the breadth of applicability of PGGs in disease modelling while providing a starting point for those interested in quantifying cooperation arising in healthcare.

Publication Type:	Article
Additional Information:	This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Subjects:	H Social Sciences > HB Economic Theory H Social Sciences > HC Economic History and Conditions H Social Sciences > HM Sociology H Social Sciences > HN Social history and conditions. Social problems. Social reform Q Science > QA Mathematics R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Departments:	School of Science & Technology School of Science & Technology > Mathematics
SWORD Depositor:	Symplectic Administrator

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