City Research Online

Abstract

The thesis is introduced as a focussing project for the development of computer aided tools for clinical decision making in the maintenance of fluid volumes and distribution in critically ill patients. Initially a conceptual approach is taken with the fluid electrolyte, acid-base balance (FAB) introduced via Systems Analysis and then via a more traditional discussion of structure, process and related abnormalities. The second distinct section considers quantitative analysis, starting with a review of extant mathematical models, and is followed by the identification and use of both statistical and mathematical techniques in an investigation into the identification and production of an appropriate quantitative tool. The third distinct section considers both practical and theoretical issues; including a microcomputer implementation of a well validated complex model, and an analysis of methodological approaches suitable for developing a model for clinical implementation.

Publication Type:	Thesis (Doctoral)
Subjects:	Q Science > QA Mathematics > QA75 Electronic computers. Computer science Q Science > QA Mathematics > QA76 Computer software R Medicine > R Medicine (General)
Departments:	School of Science & Technology > Computer Science School of Science & Technology > School of Science & Technology Doctoral Theses Doctoral Theses

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