Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas in vivo
Reyes-Aldasoro, C. C., Wilson, I., Prise, V. E. , Barber, P. R., Ameer-Beg, M., Vojnovic, B., Cunningham, V. J. & Tozer, G. M. (2008). Estimation of apparent tumor vascular permeability from multiphoton fluorescence microscopic images of P22 rat sarcomas in vivo. Microcirculation, 15(1), pp. 65-79. doi: 10.1080/10739680701436350
Abstract
To develop an image processing-based method to quantify the rate of extravasation of fluorescent contrast agents from tumor microvessels, and to investigate the effect of the tumor vascular disrupting agent combretastatin A-4-P (CA-4-P) on apparent tumor vascular permeability to 40 kDa fluorescein isothiocyanate (FITC) labeled dextran.
| Publication Type: | Article |
|---|---|
| Additional Information: | This is the accepted version of the following article: Reyes-Aldasoro, C. C., Wilson, I., Prise, V. E., Barber, P. R., Ameer-Beg, M., Vojnovic, B., Cunningham, V. J. and Tozer, G. M. (2008), Estimation of Apparent Tumor Vascular Permeability from Multiphoton Fluorescence Microscopic Images of P22 Rat Sarcomas In Vivo. Microcirculation, 15: 65–79., which has been published in final form at http://dx.doi.org/10.1080/10739680701436350 |
| Publisher Keywords: | combretastatin; multiphoton fluorescence microscopy; segmentation; tumor vascular disrupting agents; vascular permeability |
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) T Technology > T Technology (General) |
| Departments: | School of Science & Technology > Engineering School of Science & Technology > Computer Science > giCentre |
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| SWORD Depositor: |
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