City Research Online

HLA-B27 Positivity: associated health implications

Cox, C. L., Gibbons, H., Evans, P., Withers, T. and Titmus, K. (2011). HLA-B27 Positivity: associated health implications. International Journal of Ophthalmic Practice, 2(1), pp. 39-44.

Abstract

HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct association with uveitis. Although the possession of HLA-B27 positivity is not mandatory for autoimmune diseases such as uveitis to occur, HLA-B27 positivity not only makes it more likely but may modify the clinical picture in which a patient presents. In relation to assessment and diagnosis it is imperative that the medical history of patients is thoroughly examined to ensure pathological sequelae are appropriately treated. Nurses play an important role in assessing patients that have uveitis and should suspect ankylosing spondylitis or Crohn's disease may be present.

Publication Type: Article
Subjects: R Medicine > RT Nursing
Departments: School of Health Sciences > Nursing
URI: http://openaccess.city.ac.uk/id/eprint/2348
[img]
Preview
PDF
Download (389kB) | Preview
Official URL: http://www.ijop.co.uk/

Export

Downloads

Downloads per month over past year

View more statistics

Actions (login required)

Admin Login Admin Login