Preparation of a novel drug sensor using a molecular imprinted polymer approach

Wren, S., Nguyen, T.H., Gascoine, P., Lacey, D., Sun, T. & Grattan, K. T. V. (2013). Preparation of a novel drug sensor using a molecular imprinted polymer approach. Proceedings of SPIE - The International Society for Optical Engineering, 8794, doi: 10.1117/12.2025839

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Abstract

A chemical sensor for the detection of cocaine has been developed, based on a molecularly imprinted polymer (MIP) containing a fluorescein moiety as the signalling group. The fluorescent MIP was formed and covalently attached to the distal end of an optical fibre. The sensor exhibited an increase in fluorescence intensity in response to cocaine in an aqueous acetonitrile mixture. Selectivity for cocaine over codeine has been demonstrated.

Item Type: Article
Additional Information: © 2013 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: Optical fibre sensor, chemical sensor, cocaine sensor, fluorescence, molecular imprinting
Subjects: T Technology > TA Engineering (General). Civil engineering (General)
Divisions: School of Engineering & Mathematical Sciences > Engineering
URI: http://openaccess.city.ac.uk/id/eprint/2742

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