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Abstract

The objectives of this project were to develop a knowledge-based system coupled to a mathematical model for interpretation of laboratory data in an Intensive Care Unit; and to assess the benefits of such a coupling. A prototypical approach was taken to achieve these objectives.

In this thesis, basic physiology of body fluids and electrolyte is presented and several clinically oriented knowledge-based systems are reviewed. The two versions of the developed prototype are described, the problems associated with coupling symbolic programs to numerical programs are emphasised and a description of the methodology adopted is presented, as are simulation results of clinical cases. A critical discussion of the knowledge representation and reasoning methodology is given, and contributions to systems science and medical
informatics are highlighted.

Publication Type:	Thesis (Doctoral)
Subjects:	Q Science > Q Science (General) Q Science > QA Mathematics > QA75 Electronic computers. Computer science T Technology > T Technology (General)
Departments:	School of Science & Technology > Department of Computer Science School of Science & Technology > School of Science & Technology Doctoral Theses Doctoral Theses

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